In most parts of the country, the days now begin with a chill.
The hours of sunlight have decreased. Fall has arrived, so has a
new set of conditions for your skin.
The many outdoor activities of summer probably added color to
your skin. As that color begins to fade, you may notice residual brown spots and pigment
irregularities.Some of these will fade naturally as you spend less time in the sun.
We are often asked if there is a treatment for those pigment
spots that don't seem to fade. Conservative things you can do include wearing a hat
(sunscreens will not prevent these spots) and keeping yourself cool (increased body
temperature seems to play a large role in the formation and persistence of pigment spots).
Dermatologists have several options to offer you for treating
pigment irregularities. The treatments often begin with a lightening agent such as Fade
Away Gel by Cellex-C.Fading Gel produces improvement in skin spots by helping the skin
repair itself.
Fade Away Gel incorporates two patented formulations that will
help reduce the appearance of sun and age spots on the face, neck, shoulders and hands.
The original Cellex-C Complex signature ingredients join forces with a new combination of
ingredients that collectively encourage a visible lightening effect on problem areas. Fade
Away Gel promotes a clear, fresh looking complexion. Regular use of Fade Away Gel promotes
a clear, more even toned complexion in as little as 6 to 8 weeks.
To take advantage of this month's special offer on Cellex-C
Fade Away Gel, CLICK
HERE.
CELLEX-C FACTS
Cellex-C™ contains 10% L-ascorbic acid in a stable, aqueous,
acidic formulation.
1. At least 10% concentration appears to be necessary for an
optimal biological effect.
Many cosmetic products contain ascorbic acid or ascorbic acid derivatives but most contain
concentrations less than 1%.
2. L-ascorbic acid is the chemical form of ascorbic acid
used by the body.
Ascorbic acid is most commonly supplied as an equal mixture of D-ascorbic acid and
L-ascorbic acid. These forms of ascorbic acid are stereoisomers but only L-ascorbic acid
is used by the body. A concentration of 20% ascorbic acid would be necessary for an
equivalent biological effect. Cellex-C™ contains only L-ascorbic acid.
3. Ascorbic acid is notoriously difficult to stabilize.
Stabilization has precluded the use of ascorbic acid as a general cosmetic ingredient. The
Cellex-C™ formulation has succeeded in solving the stability problem. Ascorbic acid
is stable in Cellex-C™. |
4.
Acidic formulation is necessary for presenting ascorbic acid in a chemical form necessary
for getting it into skin (patent protected).
The acidic formulation of Cellex-C™ may result in a momentary stinging when the
product is applied to skin. Neutralizing the ascorbic acid will lessen the stinging but
render the ascorbic acid useless for entering the skin as well as lesson stability of the
solution.
What about ascorbic acid derivatives?
In an attempt to solve the problem of stability of ascorbic acid
in cosmetics, manufacturers have substituted analogs of ascorbic acid. These include
ascorbic acid sulfate, ascorbic acid magnesium phosphate, ascorbyl stearte, ascorbyl
palmitate and ascorbyl dipalmitate. In order for any of these compounds to work in skin
they must first get into skin and then be chemically converted by cells in the skin into
L-ascorbic acid.
1. It is very hard to get chemicals into the skin. Otherwise
we would use topical formulations to deliver all of our drugs.
Fortunately, the skin is very efficient at protecting us from foreign substances. The
patented Cellex-C™ technology for allowing ascorbic acid to enter skin is unusual.
There is no evidence that ascorbic acid derivatives enter the skin. Moreover, it would be
predicted that salts such as ascorbic acid sulfate and ascorbic acid magnesium phosphate
would not enter because of their charged nature. Esters of ascorbic acid such as ascorbyl
stearate or ascorbyl palmitate would be chemically expected to prefer the environment of a
cream to the environment of the skin and therefore not enter the skin.
2. If
the chemicals enter skin they must be altered to release the L-ascorbic acid.
This step requires cellular enzymes, which may or may not be available in skin. In the
best case, the process would not be expected to be efficient.
3. Large amounts of esters of ascorbic acid would have to enter the skin and be
converted to L-ascorbic acid to have the same potency as Cellex-C™.
For example: a molecule of ascorbyl pamitate weighs 24 times that of ascorbic acid. Even
if ascorbyl palmitate efficiently entered skin and was converted to ascorbic acid, the
optimal concentration would be expected to be about 24% ascorbyl palmitate (a formulation
nightmare). Moreover, the price of ascorbyl palmitate is approximately 3.5 times that of
ascorbic acid as a raw ingredient. The ingredient price of ascorbyl palmitate needed to
match the biological equivalence of Cellex-C would be expected to be more than eight-fold
greater than that of L-ascorbic acid, a price difficult to justify.
 |
